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What is optical activity, and how is it measured?

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Optical activity refers to the ability of certain compounds to rotate the plane of plane-polarized light. It is measured using a polarimeter, with a clockwise rotation (+) indicating dextrorotatory and a counterclockwise rotation (–) indicating laevo-rotatory.

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  1. Optical activity is a property exhibited by certain substances that rotate the plane of polarized light passing through them. This phenomenon arises due to the interaction of chiral molecules with plane-polarized light, causing a rotation in its plane of vibration. Enantiomers, non-superimposable mirror images of each other, often display optical activity. The measurement of optical activity is quantified using a polarimeter. In a polarimeter, plane-polarized light passes through a sample, and the extent of rotation is measured. The specific rotation (α) is the observed rotation corrected for concentration and path length, providing a characteristic value for a given compound.

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