Dextrorotatory isomers are denoted by placing a positive (+) sign before the degree of rotation, indicating a clockwise rotation. Laevo-rotatory isomers are denoted by a negative (–) sign before the degree of rotation, indicating a counterclockwise rotation.
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Dextrorotatory and laevo-rotatory isomers in optical isomerism are denoted by the prefixes “D” and “L,” respectively. These descriptors are based on the Latin words “dexter” (right) and “laevus” (left). In the Fischer projection, when the chiral center farthest from the carbonyl group has its substituents arranged clockwise, the compound is labeled as “D.” If the arrangement is counterclockwise, it is labeled as “L.” These labels indicate the direction in which plane-polarized light is rotated by the enantiomer. These terms help describe the absolute configuration and optical activity of chiral molecules.