Where is growth hormone secreted?

Growth hormone (GH) is secreted in the [D] Pituitary gland. Specifically, it is synthesized and released by somatotroph cells located in the anterior portion of the pituitary gland, which is situated at the base of the brain. GH secretion is regulated by the hypothalamus through the release of growth hormone-releasing hormone (GHRH) and somatostatin, which stimulate and inhibit GH production, respectively.

Once released, GH enters the bloodstream and exerts its effects on various tissues throughout the body. Its primary role is to stimulate growth, particularly during childhood and adolescence, by promoting the growth of bones and tissues. Additionally, GH influences metabolism, protein synthesis, and cell growth and repair in adults. Dysfunction in GH secretion or signaling can lead to growth disorders such as dwarfism or gigantism, highlighting the importance of proper regulation of GH secretion from the pituitary gland.