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How can carboxylic acids be reduced to primary alcohols, and which reducing agents are effective in this process?

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Carboxylic acids can be reduced to primary alcohols using lithium aluminium hydride or diborane. Diborane is preferable as it avoids reduction of other functional groups.

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  1. Carboxylic acids can be reduced to primary alcohols through various methods, with common reducing agents including lithium aluminum hydride (LiAlH₄) and sodium borohydride (NaBH₄). LiAlH₄ is a potent and versatile reducing agent that can reduce carboxylic acids to primary alcohols in a one-step process. However, it is highly reactive and must be used cautiously. NaBH₄ is milder and safer but is generally effective only for less sterically hindered carboxylic acids. The reduction involves the addition of hydride ions (H⁻) to the carbonyl carbon of the carboxylic acid, leading to the formation of a primary alcohol.

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