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Sammi
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Asked: 2021-10-14T04:49:19+00:00 In:

ELISA technique is based on the principles of antigen and antibody interaction. Can this techique be used in the molecular diagnosis of a genetic disorder, such as phenyketonuria?

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Class XII Science Biology Extra Questions
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12th Biology Terminal Exam Based Extra Questions
12th Biology Science Session 2022-23

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      Yes. One can use antibody against the enzyme (that is responsible for the metabolism of phenylalanine) to develop ELISA based diagnostic technique. The patient where the enzyme protein is absent would give negative result in ELISA when compared to normal individual.

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