Cadmium pollution is associated with (d) Itai Itai disease. This painful bone ailment emerged in Japan due to cadmium contamination from industrial sources. Prolonged exposure to cadmium-laden water and soil led to severe bone pain, skeletal deformities, and weakened bones. Unlike Minamata disease (a), which stems from mercury poisoning, and Black foot disease (b), caused by arsenic contamination, Itai Itai is directly linked to cadmium exposure. Dyslexia (c) is a learning disorder unrelated to heavy metal pollution. Addressing cadmium pollution requires stringent environmental regulations to mitigate its harmful effects on human health and ecosystems.