Chelate therapy is used to treat problems caused by toxic metal proportions in biological systems. D-penicillamine and desferrioxime B remove excess copper and iron, respectively, through the formation of coordination compounds. EDTA is employed in treating lead poisoning.
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Coordination compounds are essential in qualitative and quantitative chemical analysis. Metal ions react with ligands, forming coordination entities, which serve as the basis for detection and estimation. Reagents like EDTA, DMG, a–nitroso–b–naphthol, and cupron are commonly used.