Functional mRNA of structural genes need not always include all of its exons. This alternate splicing of exons is sex-specific, tissue-specific, and even developmental stage-specific. By such alternate splicing of exons, a single gene may encode for several isoproteins and/or proteins of similar claRead more
Functional mRNA of structural genes need not always include all of its exons. This alternate splicing of exons is sex-specific, tissue-specific, and even developmental stage-specific. By such alternate splicing of exons, a single gene may encode for several isoproteins and/or proteins of similar class. In absence of such a kind of splicing, there should have been new genes for every protein/isoprotein. Such an extravagancy has been avoided in natural phenomena by way of altemate splicing.
If histone proteins were rich in acidic amino acids instead of basic amino acids then they may not have any role in DNA packaging in eukaryotes as DNA is also negatively charged molecule. The packaging of DNA around the nucleosome would not happen. Consequently, the chromatin fibre would not be formRead more
If histone proteins were rich in acidic amino acids instead of basic amino acids then they may not have any role in DNA packaging in eukaryotes as DNA is also negatively charged molecule. The packaging of DNA around the nucleosome would not happen. Consequently, the chromatin fibre would not be formed.
Do you think that the alternate splicing of exons may enable a structural gene to code for several isoproteins from one and the same gene? If yes, how? If not, why so?
Functional mRNA of structural genes need not always include all of its exons. This alternate splicing of exons is sex-specific, tissue-specific, and even developmental stage-specific. By such alternate splicing of exons, a single gene may encode for several isoproteins and/or proteins of similar claRead more
Functional mRNA of structural genes need not always include all of its exons. This alternate splicing of exons is sex-specific, tissue-specific, and even developmental stage-specific. By such alternate splicing of exons, a single gene may encode for several isoproteins and/or proteins of similar class. In absence of such a kind of splicing, there should have been new genes for every protein/isoprotein. Such an extravagancy has been avoided in natural phenomena by way of altemate splicing.
See lessWhat would happen if histones were to be mutated and made rich in amino acids aspartic acid and glutamic acid in place of basic amino acids such as lysine and arginine?
If histone proteins were rich in acidic amino acids instead of basic amino acids then they may not have any role in DNA packaging in eukaryotes as DNA is also negatively charged molecule. The packaging of DNA around the nucleosome would not happen. Consequently, the chromatin fibre would not be formRead more
If histone proteins were rich in acidic amino acids instead of basic amino acids then they may not have any role in DNA packaging in eukaryotes as DNA is also negatively charged molecule. The packaging of DNA around the nucleosome would not happen. Consequently, the chromatin fibre would not be formed.
See less