Tertiary amines do not react with benzenesulphonyl chloride, providing a basis for distinguishing between primary, secondary, and tertiary amines. This property is employed for the separation of amine mixtures. Nowadays, p-toluenesulphonyl chloride is commonly used in place of benzenesulphonyl chloride.

The reaction of benzenesulphonyl chloride with secondary amines yields N,N-diethylbenzenesulphonamide, which lacks acidic hydrogen and is insoluble in alkali due to the absence of a hydrogen atom attached to the nitrogen.

Nitrogen orbitals in amines are sp³ hybridized, leading to a pyramidal geometry. The fourth orbital of nitrogen contains an unshared pair of electrons.

Amines are derived from ammonia by replacing hydrogen atoms with alkyl and/or aryl groups. Examples include CH₃-NH₂, CH₃-NH-CH₃, and C₆H₅-NH₂.

They find application in the dye and pigment industries and are used to produce dyed fabrics. They are useful in the synthesis of a large variety of organic compounds, especially aryl derivatives.

Quaternary Ammonium Compounds (QACs) are a type of chemical that is used to kill bacteria, viruses, and mold. There are many different types of QACs. They are often found in dis- infectants and in cleaning products that are used in ...

Benadryl contains a tertiary amino group, contributing to its antihistaminic properties.

Novocaine is used to numb pain during short medical or dental procedures. Because it’s fast-acting and doesn’t cause numbness for an extended period of time, novocaine is used for minor same-day surgery and dental procedures that take less than an ...

Adrenaline and ephedrine, both containing secondary amino groups, are used to increase blood pressure.

Some of the naturally occurring amines include alkaloids found in certain plants; catecholamine neurotransmitters (i.e., dopamine, epinephrine, and norepinephrine); and a specific chemical mediator, histamine, existing in most animal tissues. Common examples of amines include amino acids, trimethylamine, and aniline.