The term ‘Black Death’ refers to Plague. This infamous pandemic, occurring predominantly in the 14th century, was caused by the bacterium Yersinia pestis. It resulted in devastating mortality rates across Europe and Asia, leading to millions of deaths. The term ‘Black Death’ originated from the darkened appearance of the skin caused by hemorrhages under the skin in advanced stages of the disease. Unlike cancer (a), AIDS (c), and malaria (d), which are caused by different pathogens and have distinct modes of transmission, the Black Death specifically denotes the historical plague pandemic caused by Yersinia pestis.