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Gk

Anisole undergoes Friedel-Crafts reaction with alkyl halide and acyl halide in the presence of anhydrous aluminum chloride as a Lewis acid catalyst. The reaction introduces the alkyl and acyl groups at ortho and para positions.

Gk

The alkoxy group is ortho, para directing, and activates the aromatic ring in a manner similar to phenol. In the halogenation of anisole, the methoxy group activates the benzene ring, allowing bromination to occur even without an iron (III) bromide ...