Multicellular organisms typically handle waste removal through specialized organs and systems. In animals, the excretory system, including organs like kidneys and lungs, eliminates metabolic waste products. Kidneys filter blood, removing excess ions and nitrogenous waste, forming urine. Lungs expel carbon dioxide during respiration. In plants, waste removal occurs through processes like transpiration, where excess water and ions are released through stomata. Leaves and other plant organs may also shed cells to eliminate waste. These specialized structures and processes contribute to maintaining internal homeostasis by efficiently removing waste products, ensuring the proper functioning and health of multicellular organisms.